WHAT'S NEW
The Division of Surgical Science in the Department of Surgery of the Columbia University College of Physicians and Surgeons, which has been studying the biological pathways of degeneration in the human body for nearly 15 years, has recently received more than $8M from the National Institute on Aging (NIA) to study age-related cardiovascular disease.
Dr. Yan's Research Awarded $7.9M NIA Grant
Shi Du Yan, MD, MS |
Shi Du Yan, MD, MS has received $7.9M competitive renewal grant award from the National Institute on Aging to be used over a five-year period beginning on July 1, 2006.
The grant supports her research on aging and Alzheimer's disease in the Division of Surgical Science.
Dr. Schmidt Is awarded $1.25 Million JDRF Scholar Grant
Ann Marie Schmidt, MD, has been awarded a $1.25 million JDRF Scholar Grant from the Juvenile Diabetes Research Foundation in support of her research protocol "Vascular Injury in Type 1 Diabetes—A Failure of Repair: Probing the Liga."
Dr. Schmidt Is a Guest on NPR Science Friday
Ann Marie Schmidt, MD, was a guest on NPR’s “Talk of the Nation: Science Friday” on December 8, 2006, discussing her research on “the master switch for inflammation,” the RAGE cell-surface receptor.
RAGE is involved in many chronic illnesses including diabetes complications and heart disease.
Listen to the broadcast on the Talk of the Nation website.
Click here to go to the Columbia Division of Surgical Science website.
Ann Marie Schmidt, MD |
The cell-surface molecule RAGE (Receptor for Advanced Glycation Endproducts) contributes significantly to many ills, including cancer, heart disease, Alzheimer's disease, diabetes complications such as nephropathy, and a host of immune-related disorders.
For Ann Marie Schmidt, MD, Chief of the Department of Surgery's Division of Surgical Science, who has been studying RAGE for over a decade, this molecule's ability to trigger such a wide variety of disorders has revealed an unexpectedly unified picture of chronic disease and how it might be medically reversed.
After more than 15 years leading basic research on the molecule, Dr. Schmidt is now seeing her efforts pay off in development of therapies for people.
For more on this story, read coverage in the November/December, 2006 issue of Columbia University Medical Center's research newsletter, In Vivo.
Translational research is all the rage at Columbia University Medical Center. Not all the rage, perhaps, but work by the Division of Surgical Science on the Receptor for Advanced Glycation Endproducts (RAGE) represents a vitally important segment of translational research currently underway at this institution.
Publication News
The Division of Surgical Science is collaborating with the Division of Abdominal Organ Transplantation on research studies that explore the limits of liver regeneration. Initial findings were published in the February 7, 2005 issue of The Journal of Experimental Medicine.
Investigator Grant News
Collaborative Grants
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