 |











 |

Publications
Manuscripts
- Komenaka, I., Hoerig, H., and KAUFMAN, H. Immunotherapy for melanoma. Derm Clin NA 22:251-265, 2004.
- Spanknebel, K. and KAUFMAN, H.L. Surgical treatment of Stage IV melanoma. Derm Clin NA 22:240-250, 2004.
- KAUFMAN, H.L., Wei W., Manola, J., DiPaola, R.S., Ko, Y., Sweeney, C., Whiteside, T.L., Schlom, J., Wilding, G., and Weiner, L.M. Phase II Randomized Study of Vaccine Treatment of Advanced Prostate Cancer (E7897): A Trial of the Eastern Cooperative Oncology Group. J Clin Oncol 22:2122-2140, 2004.
- KAUFMAN, H.L. Manipulation of the Local Tumor Microenvironment for Cancer Immunotherapy. ASCO Education Book. 23:165-171, 2004.
- Flanagan, K., Glover, R.T., Horig, H., and KAUFMAN, H.L. Local delivery of recombinant vaccinia virus expressing secondary lymphoid chemokine (SLC) results in a CD4+ T cell dependent antitumor response. Vaccine 22:2894-2903, 2004.
- Essajee, S. and KAUFMAN, H.L. Poxvirus vaccines for cancer and HIV therapy. Exp Opin Biol Ther 4:1-14, 2004.
- Stoutenburg, J. and KAUFMAN, H.L. The role of interleukin-2 as an adjuvant for tumor vaccines. Biol Ther Cancer 2:6-10, 2004.
- KAUFMAN, H. and Disis, N. Immune system versus tumor: Shifting the balance in favor of dendritic cells and effective immunity. J Clin Invest 113:664-667, 2004.
- Gaertner, D.J., Batchelder, M., Herbst, L.H., and KAUFMAN, H.L. Administration of vaccinia virus to mice may cause bedding or contact sentinel mice to test positive for poxvirus antibody: Case report and follow-up investigation. Comparative Med 53:85-83, 2003.
- Akerele, C.E., Rybalova, I., KAUFMAN, H.L., and Mani, S. Current approaches to novel therapeutics in pancreatic cancer. Invest New Drugs 21:1-17, 2003.
- Makower, D., Rozenblitt, A., KAUFMAN, H., Edelman, M., Lane, M., Zweibel, J., and Wadler, S. Phase II clinical trial of intralesional administration of the oncolytic adenovirus, ONYX-015, in patients with hepatobiliary tumors with correlative p53 studies. Clin Cancer Res 9:693-702, 2003.
- Kwak, H., Hoerig, H., and KAUFMAN, H.L. Poxviruses as vectors for cancer immunotherapy. Curr Opin Drug Discovery Dev. 6:161-168, 2003.
- Horig, H. and KAUFMAN, H.L. Local Delivery of Poxvirus Vaccines for Melanoma. Sem Cancer Biol 13:417-422, 2003.
- Lee, C.S.D., Komenaka, I., Hurst-Wicker, K.S., Mitcham, J., and KAUFMAN, H.L. Management of metastatic malignant melanoma of the bladder. Urol 62:351xi-351xiii, 2003.
- KAUFMAN, H.L. The role of poxviruses in immunotherapy. Surgery 134:731-737, 2003.
- KAUFMAN, H.L., Cheung, K., Haskall, Z., Horig, H., Hesdorffer, C., Panicali, D., DeRaffele, G., and Spanknebel, K. Intra-lesional rF-B7.1 versus rF-TRICOM vaccine in the treatment of metastatic cancer. Human Gene Ther 14:803-827, 2003.
- Lublin, M., Bartlett, D., Danforth, D.N., KAUFMAN, H.L., Gallin, J.I., Malech, H.L., Shawker, T., Choyke, P., Kleiner, D.E., Schwartzentruber, D.J., Chang, R., Steinberg, S.M., DeCarlo, E.S., and Holland, S.M. Hepatic abscesses in patients with chronic granulomatous disease. Ann Surg 235:383-391, 2002.
- Eppler, E., Horig, H., KAUFMAN, H.L., Groscurth, P. and Filgueira, L. Antigen presentation and specific T-cell priming after transfection of human dendritic cells with mRNA encoding carcinoembryonic antigen. Eur J Cancer 38:184-193, 2002.
- KAUFMAN, H.L., Swartout, B., Horig, H., and Lubensky, I. Combination interleukin-2 and interleukin-12 induces severe gastrointestinal toxicity and epithelial cell apoptosis in mice. Cytokine 17:43-52, 2002.
- KAUFMAN, H.L., Flanagan, K., Lee, C.S.D., Perretta, D.J., and Horig, H. Insertion of interelukin-2 (IL-2) and interleukin-12 (IL-12) genes into vaccinia virus results in effective anti-tumor responses without toxicity. Vaccine 20:1862-1869, 2002.
- Huang, E.H. and KAUFMAN, H.L. CEA-based vaccines. Exp Rev Vaccines 1:49-63, 2002.
- Flanagan, K. and KAUFMAN, H.L. Chemokines and cancer. Cancer Invest 20:825-834, 2002.
- KAUFMAN, H.L., Di Vito, J., and Horig, H. Immunotherapy for pancreatic cancer: Current Concepts. Hematol Oncol Clin N Amer 16:159-197, 2002.
- KAUFMAN, H.L., Lee, C.S., and Horig. H. PSA vaccines for prostate cancer. Exp Opin Biol Ther 2:395-408, 2002.
- Soni, S., Lee, D.S., Bui, A.H., DeRaffele, G., Radel, E., and KAUFMAN, H.L. Treatment of pediatric ocular melanoma with high dose interleukin-2. J Pediatr Hematol Oncol 24:488-491, 2002.
- Wadler, S., Makower, D., Yu, B., Tan, J.Y., Rozenblit, A., KAUFMAN, H., Edelman, M., Lane, M.E., and Zweibel, J. Clinical applications of p53-directed gene therapy. Suppl Tumori 1:S21, 2002.
- Kicska, G.A., Long, L., Horig, H., Fairchild, C., Tyler, P.C., Furneaux, R.H., Schramm, V.L., and KAUFMAN, H.L. A powerful transition state analog inhibitor of purine nucleoside phosphorylase selectively inhibits human T lymphocytes. Proc Natl Acad Sci USA 98:4593-4598, 2001.
- Horig, H., Wainstein, A., Long, L., Kahn, D., Soni, S., Marcus, A., Edelmann, W., Kucherlapati, R., and KAUFMAN, H.L. A new mouse model for evaluating the immunotherapy of human colorectal cancer. Cancer Res 61:8520-8526, 2001.
- Lieberman, S. Horig, H., and KAUFMAN, H.L. Innovative treatments for pancreatic cancer. Surg Clin N Amer 81:715-739, 2001.
- KAUFMAN, H.L., DeRaffele, G., Divito, J., Horig, H., Lee, D., Panicali, D., and Voulo, M. A phase I trial of intra-lesional rV-TRICOM vaccine in the treatment of malignant melanoma. Human Gene Ther. 12:1459-1480, 2001.
- Lee, H., Woodman, S.E., Engelman, J.A., Volonte, D., Galbiati, F., KAUFMAN, H.L., Lublin, D.M., and Lisanti, M.P. Palmitoylation of caveolin-1 at a single site (cys-156) controls its coupling to the c-src tyrosine kinase. J Biol Chem 276:35150-35158, 2001.
- KAUFMAN, H.L., Conkright, W., Divito, J., Horig, H., Kaleya, R., Lee, D., Mani, S., Panicali, D., Rajdev, L., Ravikumar, T.S., Wise-Campbell, S., and Surhland, M. A phase I trial of intra-lesional rV-B7.1 vaccine in the treatment if malignant melanoma. Human Gene Ther 11:1065-1082, 2000.
- Chamberlain, R. and KAUFMAN, H.L. The future of anti-cancer vaccines. Exp Opin Pharmacother 1(4):1-12, 2000.
- Horig, H., Medina, F.A., Conkright, W.A., and KAUFMAN, H.L., Strategies for cancer therapy using carcinoembryonic antigen (CEA) vaccines. Exp Rev Mol Med 1462-3994:1-24, 2000.
- Tendler, A., KAUFMAN, H.L., and Kadish, A.S. Increased carcinoembryonic antigen (CEA) expression in cervical intraepithelial neoplasia grade 3 and in cervical squamous cell carcinoma. Human Pathol 31:1357-1362, 2000.
- Horig, H., Lee, D.S., Conkright, W., Park, D., Hasson, H., Rivera, A., LaMare, M., Tine, J., Guito, K., Tsang, K.-Y., Schlom, J., and KAUFMAN, H.L. B7.1 costimulation enhances the response of a recombinant canarypoxvirus (ALVAC) vaccine expressing human carcinoembryonic antigen (CEA). Cancer Immunol Immunother 49:504-514, 2000.
- Evans, M.E., Jordan, C.T., Chang, S.M., Conrad, C., Gerberding, J.L., KAUFMAN, H.L., Mayhall, C.G., Nolta, J.A., Pilaro, A.M., Sullivan, S., Weber, D.J., and Wivel, N,A. Clinical infection control in gene therapy: a multidisciplinary conference. Infect Control Hosp Epidemiol 21:659-673, 2000.
- Tendler, A. and KAUFMAN, H.L. Familial adenomatous polyposis and mechanisms of tumorigenesis. Einstein Q J Biol Med 15:173-178, 1999.
- Long, L., Glover, R.T., and KAUFMAN, H.L. The next generation of vaccines for the treatment of cancer. Curr Opin Mol Ther 1(1):57-63, 1999.
- Horig, H. and KAUFMAN, H.L. Current issues in cancer vaccine development. Clin Immunol 92(3):211-223, 1999.
- KAUFMAN, H.L., Rao, JB., Irvine, K., Bronte, V., Rosenberg, S.A., and Restifo, N. Interleukin-10 Enhances the Therapeutic Effectiveness of a Recombinant Poxvirus-Based Vaccine in an Experimental Murine Tumor Model. J Immunother 22(6):489-496, 1999.
- KAUFMAN, H., Roden, M., Nathanson, D., Schwartzentruber, D., and Holland, S. Splenectomy in children with chronic Mycobacterium avium complex infections. J Ped Surg 33(5):761-763, 1998.
- Chamberlain, R., KAUFMAN, H., and Danforth, D. Enterocutaneous fistula in cancer patients: Etiology, management, outcome, and impact on further treatment. Am Surgeon 64(12):1204-1211, 1998.
- KAUFMAN, H.L., Long, L., and Horig, H. The current status of cancer vaccines. Einstein Quart J Biol Med 15(3):3-23, 1998.
- KAUFMAN, H.L. The clinical application of cancer vaccines. Cliniguide Fungal Infect 9(2):6-8, 1998.
- Phelan, M., KAUFMAN, H., and Fitzpatrick, G. Jejunal enterolith small bowel obstruction: A case report and review of the literature. Surgery 121: 229-230, 1997.
- KAUFMAN, H. and Hirsch, E. Leiomyoma of the breast: A case report and review of the literature. J Surg Oncol 62: 62-64, 1996.
- Reinhorn, M., KAUFMAN, H., Hirsch, E., and Millham, F. Penetrating thoracic trauma in a pediatric population. Ann Thoracic Surg 61: 1501-5, 1996.
- KAUFMAN, H., Fischer, A., Carroll, M., and Becker, J.M. Colonic ulceration associated with non-steroidal anti-inflammatory drugs (NSAIDS). Dis Colon Rectum 39: 705-710, 1996.
- McAneny, D., Ryan, C., Beazley, R., and KAUFMAN, H. Results of a phase I clinical trial using a recombinant vaccinia-carcinoembryonic antigen (CEA) vaccine in patients with advanced colorectal cancer. Ann Surg Oncol 3(5): 495-500, 1996.
- KAUFMAN, H. and Feins, N. What is the correct operation in 1994 for cavernous transformation of the portal vein when operation seems mandatory? Coll Lett Corresp Soc Surgeons 17(4): 5-8, 1994.
- Kantor, J., Abrams, S., Irvine, K., Snoy, P., KAUFMAN, H., and Schlom, J. Specific immunotherapy using a recombinant vaccinia virus expressing human carcinoembryonic antigen (CEA). In Specific Immunotherapy of Cancer with Vaccines. Ann NY Acad Sci 690: 370-374, 1993.
- Kantor, J., Irvine, K., Abrams, S., KAUFMAN, H., DiPietro, J., and Schlom, J. Anti-tumor activity and immune responses induced by a recombinant vaccinia-carcinoembryonic antigen (CEA) vaccine. J Natl Cancer Inst 84(14): 1084-1091, 1992.
- Kantor, J., Irvine, K., Abrams, S., Snoy, P., Olsen, R., Greiner, J., KAUFMAN, H. Eggensperger, D., and Schlom, J. The immunogenicity and safety of a recombinant vaccinia virus expressing the carcinoembryonic antigen gene in a nonhuman primate. Cancer Res 52: 6917-6925, 1992.
- KAUFMAN, H., Kantor, J., and Schlom, J. A recombinant vaccinia virus expressing human carcinoembryonic antigen (CEA). Int J Cancer 48: 900-907, 1991.
- Closen, M.L., Connor, S.M., KAUFMAN, H.L., and Wojcik, M.E. AIDS in America: Death, privacy, and the law Human Rights 14(3): 26-52, 1987.
- Closen, M.L., Connor, S.M., KAUFMAN, H.L., and Wojcik, M.E. The test: Is it accurate? Is it legal? Human Rights 14(3): 30-32, 1987.
- Closen, M.L., Connor, S.M., KAUFMAN, H.L., and Wojcik, M.E. AIDS: Testing democracy- irrational responses to the public health crisis and the need for privacy in serologic testing. John Marshall Law Rev 19: 835-928, 1986.
Books/Chapters
- Bereta, M. and KAUFMAN, H.L. DNA Vaccines. In Handbook of Cancer Vaccines. Eds. Morse, M.A., Lyerly, H.K., and Clay, T.M. The Humana Press, Inc. pp. 230-246, 2003.
- KAUFMAN, H.L. and Flanagan, K. Vaccinia Virus. In emedicine: MEDICINE, OB/GYN, PSYCHIATRY, and SURGERY. Eds. Geibel, J., Marriott, H.J.L., Shulman, L.P., and Zenitz, M.E. emedicine.com Publishers. emedicine.com, 2001.
- Gargiulo, N. and KAUFMAN, H.L. Perilymph Fistula. In emedicine: MEDICINE, OB/GYN, PSYCHIATRY, and SURGERY. Eds. Geibel, J., Marriott, H.J.L., Shulman, L.P., and Zenitz, M.E. emedicine.com Publishers. Emedicine.com, 2001.
- KAUFMAN, H.L. and Schlom, J. Vaccines for Colon Cancer. In Cancer vaccines and immunotherapy. Eds. Stern, P.L., Beverley, P.L.C., and Carroll, M.W. Cambridge University Press. pp. 107-134, 2000.
- KAUFMAN, H.L. Innovative Strategies for the Treatment of Breast Cancer. In Textbook of Breast CancerA Clinical Guide to Therapy 2nd Edition. Eds. Bonadonna, G., Hortobagyi, G.N., and Gianni, A.M. Martin Dunitz Publishers. pp. 283-305, 2000.

| |
 |