 Left to right: Ben O'Mar Arrington Jr., Orin Michaeli, Scot Henry, PhD, Eugenia Nachber, James V. Guarrera, MD, Ben O'Mar Arrington |
The Molecular Therapies and Organ Preservation Lab at Columbia University focuses on topics that seek to expand bench-to-bedside translational research. The research encompasses two distinct yet intricately entwined fields. The first aspect embraces the leading edge of molecular based therapeutics and technologies including lentiviral delivery tools, combinatorial RNAi of viral infections and viral evolution. The second aspect encompasses the expanding field of organ preservation by developing paradigm breaking perfusion platforms that will allow for improved utilization of extended criteria donors and transplantation outcomes. This newly developed lab was born from the need to bridge the gap between molecular biologists and surgeons in true translational research. The lab is under the auspices of the Center for Liver Disease and Transplantation and is headed by Dr. James V. Guarrera (abdominal transplant and hepatobiliary surgeon), and Dr. Scot Henry (molecular biologist, specializing in molecular virology), this lab focuses on:
- Liver ischemia and regeneration
- Innovative approaches to the understanding of HCC and its development
- Molecular therapies of viral infections, particularly HCV
- Viral evolution in response to selection pressure
- Novel preservation methods in solid organ transplantation
- Hypothermic centrifugal machine perfusion for extended criteria donors
 James V. Guarrera, MD |
 Scot Henry, PhD |
Investigators:
James V. Guarrera, MD
Scot Henry, PhD
Staff:
Ben O'Mar Arrington, Lab Associate
Tod Brown, Lab Associate
Jason Boykin, Lab Assistant
Ben O'Mar Arrington Jr., Lab Assistant
